SNAPC5 is a subunit of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC5 binds to the proximal sequence element (PSE) common to the promotor regions of these 2 types of genes, and recruits TBP and BRF2 to the U6 snRNA TATA box.
Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Subunit:
Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC5 interacts with SNAPC4.1 Publication.
Subcellular Location:
Nuclear.
SWISS:
O75971
Gene ID:
10302
Database links:
Entrez Gene: 10302 Human
Entrez Gene: 330959 Mouse
Entrez Gene: 691501 Rat
Omim: 605979 Human
SwissProt: O75971 Human
SwissProt: Q8R2K7 Mouse
Unigene: 30174 Human
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