TAAR5 (Trace Amine Associated Receptor 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and trimethylamine receptor activity. An important paralog of this gene is TAAR9.
Function:
Orphan receptor. Ligands are likely small molecules, either sharing some similarities with trace amine as, e.g. derivatives of indolamines (such as 5-methoxytryptamine) or of phenylethylamines (such as phenylethanolamine) or being any kind of metabolite of amino acids or biogenic amine neurotransmitters.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Expressed almost exclusively in skeletal muscle and selected areas of the brain, such amygdala, hippocampus, caudate nucleus, thalamus and hypothalamus. Weak expression is also find in substantia nigra.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
O2964
Gene ID:
9038
Database links:
Entrez Gene: 768558 Chicken
Entrez Gene: 9038 Human
Entrez Gene: 215854 Mouse
Entrez Gene: 294123 Rat
Omim: 607405 Human
SwissProt: O2964 Human
SwissProt: Q5QD14 Mouse
SwissProt: Q5QD23 Rat
Unigene: 248198 Human
Unigene: 377236 Mouse
Unigene: 140571 Rat
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