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Rabbit Anti-ZNF444 antibody
This gene encodes a zinc finger protein which activates transcription of a scavenger receptor gene involved in the degradation of acetylated low density lipoprotein (Ac-LDL) (PMID: 11978792). This gene is located in a cluster of zinc finger genes on chromosome 19 at q13.4. A pseudogene of this gene is located on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Function:
Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 4 C2H2-type zinc fingers.
Contains 1 SCAN box domain.
SWISS:
Q8N0Y2
Gene ID:
55311
Database links:
Entrez Gene: 55311 Human
Entrez Gene: 72667 Mouse
Entrez Gene: 292569 Rat
Omim: 607874 Human
SwissProt: Q8N0Y2 Human
Unigene: 24545 Human
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