Rabbit Anti-SULT2B1 antibody

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Alcohol sulfotransferase; EC 2.8.2.2; HSST2; Hydroxysteroid sulfotransferase 2; ST2B1; ST2B1_HUMAN; Sulfotransferase 2B1; Sulfotransferase family cytosolic 2B member 1; SULT2B1a; SULT2B1b.

Cat:

SL12841R

Species Reactivity：

(predicted: Human,Mouse,Dog,)

Immunogen：

KLH conjugated synthetic peptide derived from human SULT2B1:111-210/365

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung.

Similarity:
Belongs to the sulfotransferase 1 family.

SWISS:
O00204

Gene ID:
6820

Database links:

Entrez Gene: 531192 Cow

Entrez Gene: 6820 Human

Entrez Gene: 54200 Mouse

Entrez Gene: 292915 Rat

Omim: 604125 Human

SwissProt: O00204 Human

SwissProt: O35400 Mouse

SwissProt: Q29YR5 Rat

Unigene: 369331 Human

Unigene: 271634 Mouse

Unigene: 100005 Rat

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