This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product. [provided by RefSeq, Aug 2009]
Function:
May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced.
Subcellular Location:
Nucleus.
Tissue Specificity:
Testis specific, expressed apparently in germ cells.
Similarity:
Belongs to the TAF1 family.
Contains 2 bromo domains.
SWISS:
Q8IZX4
Gene ID:
138474
Database links:
Entrez Gene: 138474 Human
Omim: 607798 Human
SwissProt: Q8IZX4 Human
Unigene: 591086 Human
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