TBC1D10A (TBC1 Domain Family Member 10A) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and TBC/RABGAPs. GO annotations related to this gene include GTPase activator activity and PDZ domain binding. An important paralog of this gene is TBC1D10B.
Function:
Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.
Subcellular Location:
Cell projection > microvillus. Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells.
Post-translational modifications:
Exists in both phosphorylated and non-phosphorylated state.
Similarity:
Contains 1 Rab-GAP TBC domain.
SWISS:
Q9BXI6
Gene ID:
83874
Database links:
Entrez Gene: 83874 Human
Entrez Gene: 103724 Mouse
Entrez Gene: 72968 Rat
Omim: 610020 Human
SwissProt: Q9BXI6 Human
SwissProt: P51762 Mouse
Unigene: 655273 Human
Unigene: 28140 Mouse
Unigene: 105859 Rat
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