BRINP2 is a 783 amino acid secreted protein that belongs to the FAM5 family. Existing as two alternatively spliced isoforms, BRINP2 is encoded by a gene that maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Subcellular Location:
Secreted.
Similarity:
Belongs to the FAM5 family.
Contains 1 MACPF domain.
SWISS:
Q9C0B6
Gene ID:
57795
Database links:
Entrez Gene: 57795 Human
Entrez Gene: 48843 Mouse
Entrez Gene: 286895 Rat
SwissProt: Q9C0B6 Human
SwissProt: Q6DFY8 Mouse
SwissProt: Q8K1M8 Rat
Unigene: 495918 Human
Unigene: 329579 Mouse
Unigene: 22596 Rat
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