This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several SLCterminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. [provided by RefSeq, Jul 2009]
Subcellular Location:
Cytoplasmic and Nuclear. Mainly localized in the cytoplasm particularly in the cell body and neurites of hippocampal neurons. Nuclear localization is also observed. Not detected at nuclear rim.
SWISS:
Q9H1B4
Gene ID:
55998
Database links:
Entrez Gene: 55998 Human
Omim: 300319 Human
SwissProt: Q9H1B4 Human
Unigene: 307077 Human
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