The exact function of PURG is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. PURG lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene.
Subcellular Location:
Nuclear.
SWISS:
Q9UJV8
Gene ID:
29942
Database links:
Entrez Gene: 29942 Human
Entrez Gene: 75029 Mouse
Entrez Gene: 361162 Rat
SwissProt: Q9UJV8 Human
SwissProt: Q8R4E6 Mouse
Unigene: 373778 Human
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