Rabbit Anti-SCY1 like 3 antibody

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Ezrin binding protein PACE 1; Ezrin-binding protein PACE-1; PACE 1; PACE1; PACE1_HUMAN; Protein associating with the carboxyl terminal domain of ezrin; Protein-associating with the carboxyl-terminal domain of ezrin; SCY1 like 3 (S. cerevisiae); SC

Cat:

SL8696R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SCY1 like 3:1-100/742

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

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Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the SLCterminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]

Function:
May play a role in regulating cell adhesion/migration complexes in migrating cells.

Subcellular Location:
Cytoplasm. Golgi apparatus. Cell projection > lamellipodium. Colocalized with EZR/VIL2, actin and CD44 in lamellipodia.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
May be myristoylated; myristoylation may target it to Golgi compartment. Phosphorylated.

Similarity:
Belongs to the protein kinase superfamily.
Contains 4 HEAT repeats.
Contains 1 protein kinase domain.

SWISS:
Q8IZE3

Gene ID:
57147

Database links:

Entrez Gene: 57147 Human

Omim: 608192 Human

SwissProt: Q8IZE3 Human

Unigene: 435560 Human

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