Rabbit Anti-SEC24A antibody

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protein transport protein Sec24A; SEC24 family member A S cerevisiae; SEC24 related gene family member A; SEC24 related protein A; SEC24 S cerevisiae related gene family member A.

Cat:

SL4451R

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human SEC24A:201-300/1093

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Function:
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.

Subunit:
COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. SEC24A is capable of forming heterodimers with SEC24B and SEC24C. Interacts with TMED2.

Tissue Specificity:
Expressed in fibroblasts, hepatocytes, and lymphocytes.

Similarity:
Belongs to the SEC23/SEC24 family. SEC24 subfamily.

SWISS:
O95486

Gene ID:
10802

Database links:

Entrez Gene: 10802 Human

SwissProt: O95486 Human

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