As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
Function:
As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
Subunit:
Component of the SCMC which also includes at least NLRP5 and TLE6.
Subcellular Location:
Cytoplasm. In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions.
Similarity:
Belongs to the KHDC1 family.
Contains 1 KH domain.
SWISS:
A6NGQ2
Gene ID:
441161
Database links:
Entrez Gene: 100137404 Baboon
Entrez Gene: 441161 Human
SwissProt: A9X185 Baboon
SwissProt: A6NGQ2 Human
Unigene: 671212 Human
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