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Home > Product > Antibody > Rabbit Anti-RALGPS1 antibody
Ral GEF with PH domain and SH3 binding motif 1; RalA exchange factor RalGPS1; RALGEF2; RALGPS1A; Ras specific guanine nucleotide releasing factor RalGPS1.
Cat:
SL21147R
Species Reactivity：
Mouse,(predicted: Human,Rat,Chicken,Dog,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human RALGPS1:461-557/557
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
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Unit:
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Product PDFs
Datasheet:


May be involved in cytoskeletal organization (By similarity). May also be involved in the stimulation of transcription in a Ras independent fashion (By similarity). Guanine nucleotide exchange factor for the small GTPase RALA. Six different isoforms have been described.

Function:
Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for.

Subunit:
Interacts with the SH3 domains of GRB2, NCK1, PLCG1 and SRC.

Subcellular Location:
Cell Membrane and Cytoplasmic.

Tissue Specificity:
Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus.

SWISS:
Q5JS13

Gene ID:
9649

Database links:

Entrez Gene: 9649 Human

SwissProt: Q5JS13 Human

Unigene: 648175 Human



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