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Rabbit Anti-SLC12A8 antibody
This gene is thought to be a candidate for psoriasis susceptibility. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2010]
Function:
Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation.
Subcellular Location:
Membrane.
Tissue Specificity:
Ubiquitous with very low level in normal skin.
DISEASE:
Note=SLC12A8 has been identified as a possible susceptibility gene for psoriasis mapped to chromosome 3q21 (PSORS5).
Similarity:
Belongs to the SLC12A transporter family.
SWISS:
A0AV02
Gene ID:
84561
Database links:
Entrez Gene: 84561 Human
Omim: 611316 Human
SwissProt: A0AV02 Human
Unigene: 658514 Human
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