This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Function:
Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid.
Subcellular Location:
Cell membrane. Lysosome membrane.
Similarity:
Belongs to the amino acid/polyamine transporter 2 family.
SWISS:
Q7Z2H8
Gene ID:
206358
Database links:
Entrez Gene: 206358 Human
Omim: 606561 Human
SwissProt: Q7Z2H8 Human
Unigene: 269004 Human
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