Rabbit Anti-Glycine Receptor alpha 3 antibody

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GLRA3; GLRA 3; Glra3; GLRA3_HUMAN; Glycine receptor alpha 3 polypeptide; Glycine receptor alpha 3 subunit; Glycine receptor subunit alpha 3; Glycine receptor subunit alpha-3; Ligand gated ion channel.

Cat:

SL20548R

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human Glycine Receptor alpha 3:1-100/464<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The GLRA3 gene encodes the alpha-3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composed of ligand-binding alpha and structural beta polypeptides (Kingsmore et al., 1994 [PubMed 7894176]).[supplied by OMIM, Nov 2009]

Function:
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

Subunit:
Pentamer composed of alpha and beta subunits

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely distributed throughout the central nervous system.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub-subfamily.

SWISS:
O75311

Gene ID:
8001

Database links:

Entrez Gene: 8001 Human

Entrez Gene: 110304 Mouse

Omim: 600421 Human

SwissProt: O75311 Human

SwissProt: Q91XP5 Mouse

Unigene: 413099 Human

Unigene: 307061 Mouse

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