Rabbit Anti-Phospho-delta Opioid Receptor (Ser363) antibody

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Delta Opioid Receptor (phospho S363); p-Delta Opioid Receptor (phospho S363); Delta Opioid Receptor (phospho S363); Delta Opioid Receptor (p-S363); Delta Opioid Receptor (phospho Ser363); Delta type opioid receptor; Delta type opioid receptor DOR 1; DOR 1

Cat:

SL20196R

Species Reactivity：

Human,(predicted: Mouse,Rat,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthesised phosphopeptide derived from human delta Opioid Receptor around the phosphorylation site of Ser363:TP(p-S)DG

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The opioid receptors are G-protein coupled, seven-transmembrane domain receptors for enkephalins, endorphins, and dynorphins. Three different opioid receptor subtypes (kappa , delta, and mu) were first identified by their different selectivities for various naturally occurring alkaloid opioid ligands, and subsequently confirmed by molecular cloning. The amino acid sequences of the opioid receptor subtypes are ~70% homologous, and are similar to somatostatin receptors (SSTRs) showing ~40 % homology with SSTR1. G-protein binding is thought to occur at the third intracellular loop of the opioid receptors, which is also the location of consensus sequences for phosphorylation of the receptor. Interestingly, the genes encoding the specific receptor subtypes are found on different chromosomes in both the human and mouse genomes.

Function:
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.

Subunit:
Interacts with GPRASP1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P41143

Gene ID:
4985

Database links:

Entrez Gene: 4985 Human

Entrez Gene: 18386 Mouse

Omim: 165195 Human

SwissProt: P41143 Human

SwissProt: P32300 Mouse

Unigene: 372 Human

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