In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Similarity:
Belongs to the PMG family.
SWISS:
?
Gene ID:
239933
Database links:
Entrez Gene: 643812 Human
Entrez Gene: 239933 Mouse
SwissProt: Q3LI81 Human
Unigene: 580881 Human
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