This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Probable RNA-binding protein. May be involved in pre-mRNA splicing process.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the splicing factor SR family.
Contains 2 RRM (RNA recognition motif) domains.
SWISS:
Q86U06
Gene ID:
55147
Database links:
Entrez Gene: 55147 Human
SwissProt: Q86U06 Human
Unigene: 4997 Human
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