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Rabbit Anti-Uridine Phosphorylase 1 antibody
The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA
Function:
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Subunit:
Homodimer.
Similarity:
Belongs to the PNP/UDP phosphorylase family.
SWISS:
Q16831
Gene ID:
7378
Database links:
Entrez Gene: 7378 Human
Omim: 191730 Human
SwissProt: Q16831 Human
Unigene: 48848 Human
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