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Rabbit Anti-HORMAD1 antibody
This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Function:
HORMAD1 is a cancer/testis (CT) antigen; it is expressed strongly in testis, where it is increased in cancer and weakly in placenta. HORMAD1 shows homology to a yeast meiosis specific protein.
Subcellular Location:
Nuclear
SWISS:
Q9D5T7
Gene ID:
67981
Database links:
Entrez Gene: 529615
Cow
Entrez
Gene: 67981 Mouse
Entrez
Gene: 16872 Human
Omim: 609824 Human
SwissProt: Q2KIY6 Cow
SwissProt: Q9D5T7 Mouse
SwissProt: Q86X24 Human
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