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Rabbit Anti-Nucleoplasmin 2 antibody
NPM2 (Nucleophosmin/Nucleoplasmin 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and enzyme binding. An important paralog of this gene is NPM1.
Function:
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.
Subunit:
Homopentamer, when bound to H2A-H2B dimers only. Homodecamer of two stacked pentamers, when bound to H2A-H2B dimers and H3-H4 tetramers simultaneously (By similarity).
Subcellular Location:
Nucleus. Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.
Similarity:
Belongs to the nucleoplasmin family.
SWISS:
Q80W85
Gene ID:
32888
Database links:
Entrez Gene: 10361 Human
Entrez Gene: 32888 Mouse
Omim: 608073 Human
SwissProt: Q86SE8 Human
SwissProt:
Q80W85 Mouse
Unigene:
131055 Human
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