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Rabbit Anti-Cytokeratin 15 antibody
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq].
Subunit:
Heterotetramer of two type I and two type II keratins.
Tissue Specificity:
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.
Similarity:
Belongs to the intermediate filament family.
SWISS:
P19012
Gene ID:
3866
Database links:
Entrez Gene: 3866 Human
Entrez Gene: 16665 Mouse
Entrez Gene: 287700 Rat
Omim: 29630 Human
SwissProt: P19012 Human
SwissProt: Q61414 Mouse
SwissProt: Q6IFV3 Rat
Unigene: 654570 Human
Unigene: 88010 Mouse
Unigene: 153568 Rat
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