Rab 3A; RAB 3A member RAS oncogene family; Rab3a; RAB3A member RAS oncogene family; RAB3A_HUMAN; RAS associated protein RAB 3A; RAS associated protein RAB3A; Ras related protein Rab 3A; Ras related protein Rab3A; Ras-related protein Rab-3A.
Cat:
SLM51311M
Species Reactivity：
Mouse,(predicted: Human,Rat,)
Immunogen：
Recombinant human RAB3A
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Monoclonal
Isotype：
IgG1,k
Applications：
WB=1:200-1000ELISA=1:5000-10000ICC=1:100-500IF=1:20-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Mouse
Product Overview：
Sample: Cerebellum (Mouse) Lysate at 40 ugCerebrum (Mouse) Lysate at 40 ugPrimary: Anti- RAB3A (SLM51311M) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilutionPredicted band size: 25 kDObserved band size: 25 kDSample: Cerebrum (Mouse) Lysate at 40 ugPrimary: Anti-RAB3A (SLM51311M) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti- Mouse IgG at 1/20000 dilutionPredicted band size: 25 kDObserved band size: 25 kD
RAB3A (RAB3A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB3A include Growth Hormone Deficiency, Isolated, Type Ii. Among its related pathways are Innate Immune System and Neurotransmitter Release Cycle. GO annotations related to this gene include GTP binding and protein SLCterminus binding. An important paralog of this gene is RAB3C.
Function: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Subunit: Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A and RPH3AL. Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3 (By similarity).
Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).
Tissue Specificity: Specifically expressed in brain.
Similarity: Belongs to the small GTPase superfamily. Rab family.
Sample:
Cerebellum (Mouse) Lysate at 40 ug
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti- RAB3A (SLM51311M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 25 kD
Observed band size: 25 kD
Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-RAB3A (SLM51311M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti- Mouse IgG at 1/20000 dilution
Predicted band size: 25 kD
Observed band size: 25 kD
