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Home > Product > Antibody > Mouse Anti-Myoglobin antibody
MYO; MB; MGC13548; PVALB; MYG_HUMAN.
Cat:
SLM41107M
Species Reactivity：
Rat,(predicted: Human,)
Immunogen：
Purified Human Myoglobin (Natural Human Myoglobin protein)
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Monoclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Mouse
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Myoglobin) Polyclonal Antibody, Unconjugated (SLM41107M) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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Unit:
Price: $
Product PDFs
Datasheet:


Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Function:
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Similarity:
Belongs to the globin family.

SWISS:
P02144

Gene ID:
4151

Database links:

Entrez Gene: 4151 Human

Entrez Gene: 17189 Mouse

Entrez Gene: 59108 Rat

Omim: 160000 Human

SwissProt: P02144 Human

SwissProt: P04247 Mouse

SwissProt: Q9QZ76 Rat

Unigene: 517586 Human

Unigene: 404074 Mouse

Unigene: 40511 Rat



Picture

Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Myoglobin) Polyclonal Antibody, Unconjugated (SLM41107M) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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