Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Clonality：
Monoclonal
Isotype：
IgG1
Applications：
Flow-Cyt=20μl/Testnot yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Mouse
Product Overview：
Flow cytometry staining of normal human peripheral blood cells with CD3/PerCP(SLM30061M-PerCP)(Red histogram) or Mouse IgG1 Isotype Control PerCP (C03-11003)(Blue histogram). Total cells were used for analysis.
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Function: The CD3 complex mediates signal transduction.
Subunit: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
Subcellular Location: Membrane; Single-pass type I membrane protein.
Flow cytometry staining of normal human peripheral blood cells with CD3/PerCP(SLM30061M-PerCP)(Red histogram) or Mouse IgG1 Isotype Control PerCP (C03-11003)(Blue histogram). Total cells were used for analysis.
