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GLHA_HUMAN; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha (CG-alpha); Follicle-stimulatin
Cat:
SLM2026M
Species Reactivity:
Human,
Immunogen:
Natural human hCG protein
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Monoclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Mouse
Product Overview:
Measured by its binding ability in a indirect ELISA. Immobilized Human HCG alpha protein, HisTag (Cat. SL43085P) at 2 μg/mL (100 μL/well) can bind Mouse Anti-Human HCG alpha Antibody, the EC50 is 40.93 ng/mL.
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Unit:
Price: $
Product PDFs
Datasheet:


The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Function:
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Subcellular Location:
Secreted.

Similarity:
Belongs to the glycoprotein hormones subunit alpha family.

SWISS:
P01215

Gene ID:
1081

Database links:

Entrez Gene: 1081 Human

SwissProt: P01215 Human



HCG是由胎盘合体滋养层细胞产生的一种糖蛋白激素,主要用于胎盘滋养细胞和生殖细胞肿瘤如葡萄胎、绒癌的诊断和辅助诊断。 Picture

Measured by its binding ability in a indirect ELISA. Immobilized Human HCG alpha protein, HisTag (Cat. SL43085P) at 2 μg/mL (100 μL/well) can bind Mouse Anti-Human HCG alpha Antibody, the EC50 is 40.93 ng/mL.
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